Location
London

Hours
Full Time (hours not specified)

Salary
£56,276 per annum

About the Role
Work autonomously to manage a large caseload of patients, ensuring a professional duty of care to patients and their families. Operate within EU clinical trial directives in accordance with ICH GCP (International Conference on Harmonisation and Good Clinical Practice), ensuring strict adherence to clinical trial protocols at all times. Identify suitable patients for clinical trial entry by attending clinics, screening notes, consultant referrals, and Multidisciplinary Team (MDT) meetings. Participate in the informed consent process, providing support and acting as a resource for patients and their families. Coordinate the research patient pathway from screening through trial closure, including creation of prompts at trial setup stages. Ensure precautions to minimise cross-infection risks related to safe disposal of body fluids and blood products. Support administration of trial drugs, monitor and report side effects as outlined in protocols, in collaboration with local nursing teams. Maintain accurate patient records and ensure all relevant information is documented in medical and nursing notes. Responsible for accurate completion of Clinical Report Forms (CRFs) and for collection, coordination, and computerisation of clinical trial data. Stay current with best practices in cannulation, phlebotomy, care of patients with Central Venous Access lines, and handling and administration of systemic anti-cancer therapy (SACT) and Investigational Products (IP). Identify and implement strategies to recruit patients to clinical trials and support less experienced team members in these efforts. Act as a role model for excellence in oncology/haematology research and serve as keyworker for trial patients throughout their treatment, liaising with medical and Clinical Nurse Specialist (CNS) teams. Facilitate signposting and referral of trial patients to supportive care services. Review trial protocols to identify risks and resource implications, attend pre-study visits, and assist in feasibility assessments to ensure patient safety. Liaise with medical teams, sponsors, Clinical Trial Set Up staff, and Team Leads to coordinate on-study treatment and follow-up. Assist with submissions to Research & Development departments and manage protocol amendments, disseminating information appropriately. Supervise the research team in data collation and provide information for invoicing where applicable. Build strong professional relationships across departments to promote a positive working environment. Educate medical and nursing personnel about the clinical trial portfolio. Present research findings within the Trust and external networks. Manage clinical incidents effectively, reporting to the Cancer Clinical Governance Team and following up to resolution. Maintain ongoing communication with the Clinical Research Matron and Clinical Trials Manager. Attend monthly portfolio performance review meetings to identify and address issues. Provide cover for team members during leave periods. Assist in recruitment and selection of research staff Trust-wide. Contribute to business planning to ensure the research team is well structured and resourced. Lead service development initiatives for the research team, directorate, and Trust. Develop and implement the key worker concept within the Research Team. Drive strategies to maintain and increase patient recruitment into cancer clinical trials in line with the Cancer strategy. Innovate and contribute to network-wide clinical and research policies and procedures. Collaborate with the team leader to meet accrual targets for NCRN and commercial trials and address shortfalls. Implement quality assurance strategies and systems. Attend training programmes, investigator meetings, and conferences as part of professional development. Take personal responsibility for professional growth and keep up to date with research developments. Prepare posters and research papers for meetings, conferences, and publications. Represent the research team at local and national forums. Participate in service development and mentor/support team members. Engage in clinical supervision as both supervisor and supervisee according to NMC guidelines. Undertake regular performance reviews and ensure team adherence to Trust policies. Act up for Team Lead and Research Matron as required.

Experience
Proven experience managing clinical trial patients autonomously within oncology/haematology research settings. Knowledge of EU clinical trial directives and ICH GCP guidelines. Experience in patient recruitment, informed consent processes, and clinical trial coordination. Skilled in cannulation, phlebotomy, and care of patients with Central Venous Access lines. Familiarity with systemic anti-cancer therapy (SACT) and Investigational Products (IP) administration. Experience supervising research teams and managing clinical incidents. Ability to liaise effectively with multidisciplinary teams and external sponsors.

About you
Highly motivated and professional with excellent organisational and communication skills. Able to work independently and as part of a team. Strong leadership qualities with the ability to mentor and support colleagues. Committed to maintaining high standards of patient care and research integrity. Adaptable and proactive in service development and quality assurance initiatives. Willingness to engage in continuous professional development and represent the Trust at various forums.

Qualifications
Registered Nurse with relevant clinical research experience. Training and certification in Good Clinical Practice (GCP). Evidence of ongoing professional development in clinical research and oncology/haematology nursing. Experience or training in clinical supervision and performance management is desirable.